Global Protein Sequencing Market By Products & Services (Reagents & Consumables, Instruments , Analysis Product , Protein Sequencing Services) By Technology (Mass Spectrometry , Edman Degradation) Growth, Future Prospects & Competitive Analysis, 2016 – 2030

Key Highlights of the report

How are the major segments performing in the Protein Sequencing Market?

• The protein sequencing services segment dominated the global market in 2021, owing to the benefits of the protein sequencing-based methodology for preliminary drug development procedures, technological advancements, and rising global demand for targeted drug therapy.
• In 2021, the Edman degradation technology segment accounted for the major global market revenue share. The Edman degradation method is a sensitive and straightforward method for determining the location of phosphoramide acids in an isolated phosphopeptide. Edman degradation is a useful method for analyzing protein sequences.
• In 2021, the biopharmaceuticals application segment accounted for a large global protein sequencing market share. Protein sequencing, particularly mass spectrometry, is used in the pharmaceutical industry as part of drug discovery and development. As a result, the increasing adoption of biomolecule and drug component analysis propels the segment forward.

What is the Market Size of Protein Sequencing regarding value?

The global protein sequencing market is anticipated to grow at a substantial CAGR of 3.2% in the upcoming years. The global Protein Sequencing industry was estimated to be worth USD 1.1 billion in 2021 and was expected to be worth USD 1.32 billion by 2028.

Which region dominated the protein sequencing market?

The North American region was expected to account for a large share of the global protein sequencing market in 2021. This can be attributed to the region’s well-established academic institutions, research centers, and increased R&D funding opportunities. The region’s government funding for organizations is quite substantial. For instance, the UniProt portal provides free access to resources for protein sequencing and functional data. Several government organizations support this portal, including the National Heart, Lung, & Blood Institute, National Human Genome Research Institute (NHGRI), and the National Eye Institute.

How is US Market Performing in the protein sequencing market?

The United States has the largest North American protein sequencing market share. Major pharmaceutical and biotechnology companies are fueling market expansion in the nation with rising expenditures for research and development. The growing emphasis on structure-based drug design, combined with an increase in proteomic research, is driving the protein sequencing market in the United States. Creating data analysis tools for protein sequencing promotes market expansion in the North American region.

What is the competitive environment of the protein sequencing market?

The key industry participants constantly implement various growth strategies to stay ahead of the competition. These players use innovations, mergers, acquisitions, and collaborative partnerships to prosper in the fiercely competitive market. The top players in the market are also consistently focusing on R&D to give industries the most efficient and cost-effective solutions. Increased strategic initiatives by bio-therapeutics players are expected further to support the growth of the protein sequencing market. For example, Generate Biomedicines announced in November 2021 that it raised USD 370 million in Series B funding to support the development of a drug-generation platform. The platform’s goal is to understand genetic coding in protein functionality better. It is a game-changing method for drug development and protein therapeutics.

Executive Summary

What are the key trends or recent developments in the Protein Sequencing Market?

• Amgen and Generate Biomedicines announced a collaboration in January 2022 to discover and develop protein-based therapeutics in various application fields.
• Charles River Laboratories (US) opened its Biologics Validation Solutions facility in Pennsylvania (US) in March 2018 to help develop, characterize, and release biologics and biosimilars.
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What are all the technical developments in the Protein Sequencing Market?

The institutions are developing protein sequencing technologies through extensive research and development. For instance, in January 2022, University of Texas researchers reported creating a workable method for single-molecule protein sequencing. As a result, technological advances in protein sequencing techniques are expected to drive market growth. Moreover, several companies are developing novel technologies to make protein sequencing easier for service providers. For example, in September 2022, NVIDIA Corporation announced the integration of its NeMo LLM cloud service with BioNeMO, which provides researchers with access to biology language models and pre-trained molecular biology. These services support research interaction and modify data and proteins for various uses, such as drug discovery.

Which are the key investments by the protein sequencing market players?

The advancement of non-commercial and commercial specific antibodies research, combined with increasing investment in proteomics by biotechnology companies, is expected to become a major growth determinant of the protein sequencing market. Increased government and corporate funding and grants for biomedical R&D are expected to impact sequencing usage significantly. According to a WHO report released in January 2022, 11 funders gave approximately 80,178 grants to biomedical research in 2019. 69.4% of the grants were for research, while 19.5% were for training. Furthermore, organizations in the United States received about 75% of the total grants. Federal funding in the United States has prompted end-user demand for protein sequencing.

Some major players in the protein sequencing market are Charles River Laboratories, Shimadzu Corporation, Agilent Technologies, Thermo Fischer Inc, Selvita, Rapid Novor Inc, SGS S.A., Proteome Factory, Bioinformatics solution, and Water Corporation.

What are the Major Driving Factors for the Protein Sequencing Market?

Protein sequencing has grown in popularity as a high-throughput proteomic technique with many applications. The increasing use of target-based drug design by pharmaceutical and biotechnology firms is expected to drive the global protein sequencing market in the coming years. Growing research into genetically modified organisms and technological advancements are expected to propel growth in the target market for protein sequencing for genetic engineering applications over the upcoming years. Other factors anticipated to contribute to the target market’s growth over the projection period include analytical techniques and clinical mass spectrometry advancements.

What are the Major Risks for the Protein Sequencing Market?

Higher infrastructure costs significantly constrain the target market’s growth. The need for qualified researchers and laboratory personnel and preparing pure protein samples are additional factors posing challenges to the global protein sequencing industry’s expansion. Besides, the equipment needed for protein sequencing requires complicated maintenance and operation. A mass spectrometer may need troubleshooting quickly, even if properly maintained to function as needed. This is one of the operational difficulties the end users encounter.

Which is the key application in the protein sequencing market?

The biopharmaceutical industry currently holds the largest market share and is expected to increase significantly and monopolize the global protein sequencing market during the forecast period. Protein sequencing, particularly mass spectrometry, is used in the pharmaceutical sector to aid drug discovery and development. As a result, the increasing adoption of biomolecule and drug component analysis is boosting the segment forward. Advanced mass spectrometry systems provide high throughput and an optimized testing environment. As a result, there is a growing demand for such advanced products in these applications.

How is the protein sequencing market performing in regions?

North America held a dominant position in the global protein sequencing market in 2021 due to increased funding for proteome research from government and businesses and important key players in nations like the United States and Canada. The reliance of market companies on structure-based drug discovery is growing, and the development of technologically advanced protein sequencing analytical methods and techniques is further boosting regional demand. Furthermore, rising R&D spending by major pharmaceutical and biotechnology companies, lower sequencing costs, and an increase in sequencing service providers are expected to drive the regional protein sequencing market in the coming years.

Moreover, Asia Pacific is expected to grow fastest during the forecast period owing to the growing implementation of mass spectrometry-based technologies in China and India for various protein sequencing applications. Genomics and proteomics research is receiving more attention, and academic institutions are taking more initiatives to develop protein-based therapeutics, opening up significant growth opportunities for the Asia Pacific market. Government regulations in this region are favorable owing to the greater adoption of protein sequencing techniques.

What is the regulatory landscape for the protein sequencing market?

Proteome sampling technology advancements are expected to support the technique’s growth in the protein sequencing market. The legislation governing intellectual property, including protein sequencing patents, must be formal. In Australia, for example, the jurisdiction significantly impacts the validity of a sequencing patent. The inability of academic institutions to conduct R&D on the creation of new technologies is a result of the need for patent regulations.

What are the major players planning for the future of the protein sequencing market?

Protein sequencing is increasingly in demand owing to growing genomics and proteomics research and an increase in the need for protein-based medicines globally. For example, Amphista Therapeutics and Bristol Myers Squibb announced a partnership to discover and develop small molecule protein degraders in May 2022. Bristol Myers Squibb will likely receive an exclusive license to manufacture and commercialize the product. As a result, the emerging demand for protein degradation is expected to broaden the application scope of protein sequencing.

Segmentation of Global Protein Sequencing Market-

Global Protein Sequencing Market – By Products & Services

• Reagents & Consumables
• Instruments
• Analysis Product
• Protein Sequencing Services

Global Protein Sequencing Market – By Technology

• Mass Spectrometry
• Edman Degradation

Global Protein Sequencing Market – By Application

• Biopharmaceuticals
• Biotechnology Research

Global Protein Sequencing Market – By Region

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • South-east Asia
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa