Epigenetics Market By Product (Kits, Reagent, Enzymes, Instruments and Bioinformatics Tools), By Technology (DNA Methylation, Histone Modification and Other), By Application (Cancer, Metabolic Diseases, Immune Diseases, Cardiovascular Diseases and Other) - Growth, Future Prospects and Competitive Analysis, 2018 – 2026

Epigenetics is a term referred to the study of long-term changes in gene expression, which may or may not be heritable, and do not involve the changes to the DNA sequence. It is estimated that epigenetics market will grow at a double digit CAGR over the forecast period from 2018 to 2026. Some major factors assisting the market growth are increasing awareness about epigenetics in different medical fields, growing funding for research and development activities and increasing prevalence of complex diseases such as cancer. Conversely, lack of widespread availability of skilled professionals and existence stringent regulatory framework governing the field of epigenetics and genetic research restrain the market growth. 

The global epigenetics market is classified on the basis of products, technologies and applications. Market estimation and forecast analysis for each of these classes for the period from 2016 to 2026 are included in this report study along with respective CAGRs during the forecast from 2018 to 2026. On the basis of product types, the epigenetics market is categorized as kits (ChiP-Seq Kits, whole-genome amplification kits, 5-HMC and 5-MC analysis kits and other epigenetics kits), reagent, enzymes (DNA-modifying enzymes, protein-modifying enzymes and RNA-modifying enzymes), instruments and bioinformatics tools. Based on applications, this market segmented as cancer, metabolic diseases, immune diseases, cardiovascular diseases and other applications. DNA methylation, histone modification and other techniques are the technologies studied in this report. 

The global epigenetics market report also studies the following regional markets:

• North America
  
  • U.S.
  • Canada
• Europe
  
  • U.K.
  • Germany
  • Rest of Europe
• Asia Pacific
  
  • Japan
  • China
  • Rest of Asia Pacific
• Latin America
  
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East and Africa
  
  • GCC
  • Rest of MEA
  •  

Alongside the numeric data (market size and forecast), subjective informational sets and assessment tools are also incorporated in this report to cover in-depth analysis of general market circumstance and future projections. Information such as epigenetics market drivers, challenges and opportunities cover insights related to current trends in the global epigenetics market. Attractive investment proposition, company profiles and market positioning of key manufacturers provide insights on the competitive situation of the global epigenetics market. This report also presents company profiles segment which features key data related to the prominent players involved in epigenetics market.

Based on the applications, the global epigenetics market is segmented as follows:

• Cancer
• Metabolic Diseases
• Immune Diseases
• Cardiovascular Diseases
• Others
•  

From the last few decades, the demand for epigenetics study in characterization of various diseases has increased in the field of drug discovery and life science research. Applicability of epigenetics study for complex diseases such as cancer, behavior plasticity, autoimmune diseases, neurodegenerative and psychological disorders, addiction etc. has considerably increased in the market. In 2017, cancer is the major revenue-generating segment in the global epigenetics market because the reported evidence that epigenetic modifications have a considerable effect on cancer development and therefore management. Non-oncology segment of epigenetics market comprises metabolic diseases, infectious diseases, cardiovascular diseases, and others. Metabolic diseases was the largest share holding sub-segment in the year 2014 at over 32.0% due to the high impact of high-fat diet on DNA modifications and epigenetic regulation of metabolism.

However, the cardiovascular disorders segment is expected to be the fastest growing segment over the forecast period owing to the emergence of technologies such as microRNA modifications in diagnosis and treatment of cardiovascular disorders. Other factors such as increase in prevalence of different forms of cancer, strong product pipeline and higher number of unmet needs are fueling the growth epigenetics in cancer.

Based on the technology types, the global epigenetics market is segmented as follows:

• DNA Methylation
• Histone Modification
• Other Techniques 
•  

Epigenetics is the study of modification in gene expression that does not involve changes to the genetic code. The epigenetics market will grow significantly over the forecast period owing to its robustness. Furthermore, increasing applicability of epigenetics in targeted therapy and personalized medicine would influence the market growth over the forecast period. DNA methylation, non-coding RNA associated gene silencing and histone modification play an essential role in initiating and sustaining epigenetic changes. The introduction of technological advancement such as Methylation Sensitive PCR (MSP) and rapid adoption of these products to improve diagnostics efficiency are some factors attributing for its largest share. 

It is observed that the demand for DNA methylation technique was the highest in market as it is a rapid and accurate technique for whole genome analysis. DNA methylation technique is used in the preparation of DNA for methylation analysis; it includes the selection of methylated DNA, enzymatic compartmentalization by methylation sensitive enzymes, and biochemical treatment of the DNA. DNA methylation technique has great potential in understanding the functional mechanisms in complex disease and personalized drug development. Moreover, methylation plays a fundamental role in cell divisions, differentiation, apoptosis, growth factor response, detoxification, metastasis etc. that have promoted huge advances in the early detection of cancer.

For the purpose of this study, the global epigenetics market is categorized as follows:

• North America
  • United States
  • Canada
• Europe
  • U.K.
  • Germany
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East and Africa
  • GCC
  • Rest of Middle East and Africa

North America is the current geographical leader in the worldwide epigenetics market. Some key factors such as increase in demand for personalized medicines coupled with greater awareness between both patients and caregivers play a vital role in the dominance of this region. North America also houses some of the largest pharmaceuticals manufacturers which are actively involved in research and development of development of novel drugs in oncology and non-oncology treatments. 

Furthermore, some other factors such as well-developed healthcare infrastructure, rapid rise in popularity of epigenetics, higher prevalence of complex diseases and early acceptance of advanced technologies are fueling the market growth in North America. On the other hand, evolving regulatory policies in key counties such as China and India, growing research and development outsourcing and increasing population of patients with chronic diseases have a supportive role in the high market growth rate in Asia Pacific. Collaborations between domestic life science companies and international pharmaceuticals companies for the development of better therapeutics also facilitate the growth of this region.